Table 3.
Baseline characteristics according to pre-percutaneous coronary intervention TIMI 3 or <3 flow in the two treatment groups
| Pre-PCI TIMI 3 |
Pre-PCI TIMI <3 |
|||||
|---|---|---|---|---|---|---|
| Primary PCI (n=124) | TNK+PCI (n=353) | p-value | Primary PCI (n=689) | TNK+PCI (n=451) | p-value | |
| Age (years) | 60 (51–70) | 60 (51–70) | 0.939 | 59 (51–69) | 61 (53–70) | 0.153 |
| Women | 33.1 | 22.4 | 0.018 | 20.5 | 23.9 | 0.164 |
| Weight (kg) | 74 (65–84) | 77 (68–85) | 0.126 | 78 (70–86) | 77 (67–87) | 0.814 |
| Previous CHF | 2.4 | 0.9 | 0.180 | 1.3 | 0.9 | 0.517 |
| Previous MI | 12.9 | 12.8 | 0.981 | 9.9 | 11.9 | 0.300 |
| Previous PCI | 6.5 | 9.4 | 0.321 | 8.5 | 7.4 | 0.519 |
| Previous CABG | 3.2 | 2.0 | 0.433 | 1.5 | 2.0 | 0.485 |
| Hypertension | 46.8 | 47.3 | 0.918 | 46 | 46.8 | 0.797 |
| Diabetes | 24.2 | 16.5 | 0.057 | 13.5 | 18.4 | 0.026 |
| Current smoker | 47.1 | 42.8 | 0.414 | 49.2 | 47.3 | 0.541 |
| Heart rate (bpm) | 75 (65–90) | 72 (60–84) | 0.031 | 75 (64–85) | 74 (62–85) | 0.359 |
| Systolic blood pressure (mmHg) | 130 (115–150) | 138 (120–154) | 0.072 | 135 (120–150) | 130 (117–148) | 0.062 |
| Symptom onset to initial treatment (min) | 139 (95–215) | 149 (100–225) | 0.312 | 145 (100–215) | 155 (110–221) | 0.143 |
| Killip class >I | 3.3 | 6.5 | 0.490 | 7.7 | 11.1 | 0.183 |
| Anterior MI location | 52.9 | 46.1 | 0.196 | 46.9 | 51.9 | 0.100 |
Values are% or median (interquartile range). CABG, coronary artery bypass graft; CHF, congestive heart failure; MI, myocardial infarction; PCI, percutaneous coronary intervention; TIMI, thrombolysis in myocardial infarction; TNK, tenecteplase.