Table 2.
Results of multivariate analyses of the incidence of pulmonary embolism after major orthopedic surgery. Part A – results from the core model not including the metabolic syndrome related covariates. Part B – results from three models combining the covariates from the core model and covariates related to metabolic syndrome: *dichotomous indicator of metabolic syndrome; †the number of metabolic syndrome components treated as ordinal covariate; ‡individual metabolic syndrome components considered simultaneously
| Covariate/base comparison | Odds ratio (95% confidence interval) | P | Increase in log-likelihood |
|---|---|---|---|
| A |
|||
| Age (yrs) |
Overall |
0.007§ |
|
| 50-60 /<50 |
1.43 (0.52- 3.90) |
0.486 |
|
| 60-70 /<50 |
1.80 (0.69 - 4.72) |
0.232 |
|
| 70-80 /<50 |
2.96 (1.15- 7.63) |
0.025§ |
|
| >80 /<50 |
3.74 (1.33- 10.48) |
0.012§ |
|
| Knee/hip |
2.77 (1.73- 4.45) |
<0.001§ |
|
| Bilateral knee/unilateral knee |
2.19 (1.34- 3.57) |
0.002§ |
|
| Congestive heart failure |
3.12 (1.46- 6.68) |
0.003§ |
|
| Year of surgery |
Overall |
0.051§ |
|
| 2002/2001 |
2.02 (0.74 - 5.51) |
0.170 |
|
| 2003/2001 |
2.06 (0.82 - 5.17) |
0.124 |
|
| 2004/2001 |
3.41 (1.42 - 8.17) |
0.006§ |
|
| 2005-6/2001 |
2.64 (1.10 - 6.32) |
0.030§ |
|
| B |
|||
| Metabolic syndrome* |
1.61 (1.01 - 2.56) |
0.043§ |
1.90 |
| Number of metabolic syndrome components (0-4)† |
1.23 (1.02 - 1.48) |
0.028§ |
2.37 |
| Hypertension‡ |
0.93 (0.61 - 1.42) |
0.736 |
|
| Dyslipidemia‡ |
1.09 (0.68 - 1.72) |
0.728 |
|
| Body mass index ≥30 kg/m2‡ |
2.19 (1.42 - 3.36) |
<0.001§ |
|
| Dysglycemia‡ | 0.97 (0.57 - 1.65) | 0.916 |
§Statistically significant <0.05.