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. Author manuscript; available in PMC: 2013 Sep 3.
Published in final edited form as: Dig Dis Sci. 2012 May 10;57(9):2371–2378. doi: 10.1007/s10620-012-2183-7

Fig. 5.

Fig. 5

Adenine up-regulates α-SMA and collagen 1. a and b Adenine up-regulates α-SMA in primary rat HSC. c Adenine increases production of collagen 1 mRNA by T-6 cells and rat HSC (* P < 0.01, ** P < 0.01). d The ability of adenine to up-regulate collagen 1 mRNA is abolished by adenine receptor specific SiRNA (* P < 0.01). All experiments were repeated at least three times