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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Int J Gynecol Cancer. 2013 Jun;23(5):815–822. doi: 10.1097/IGC.0b013e31828f7a24

Table 4. Hazard ratio between the nadir CA-125 and survival.

Author,
Year
N Country cutoff (u/ml) HR,OS HR,PFS
Markman,2006 384 USA <10, N/A reference
11-20, N/A 1.51(0.002)
21-35 N/A 2.32(0.001)
Juretzka,2007 241 USA 12 1/1.41(1.044-1.904) N/A
Prat,2008 96 Spain 10 6.0(0.0002) 2.15(0.0081)
Park,2011 267 Korea <12 reference N/A
12-18 1/1.68(1.11-2.56) N/A
18-35 1/2.85(1.70-4.76) N/A
Altena,2010 331 Netherlands 5 1.62 (95% CI, 1.03-2.54) 1.75 (95% CI, 1.20-2.57)
Kim,2008 123 Korea <10, reference reference
10-21, 1/2.396(1.270-4.521) 1/2.508(1.062-5.921)
>21 1/5.384(2.510-11.549) 1/3.929(1.140-8.607)
Crawford,2005 78 UK 10 1/D.1336(p<0.001) N/A
Grad,1994 223 Australia 15 1/3.23(2.62-3.99) N/A