Table 4. Hazard ratio between the nadir CA-125 and survival.
Author, Year |
N | Country | cutoff (u/ml) | HR,OS | HR,PFS |
---|---|---|---|---|---|
Markman,2006 | 384 | USA | <10, | N/A | reference |
11-20, | N/A | 1.51(0.002) | |||
21-35 | N/A | 2.32(0.001) | |||
Juretzka,2007 | 241 | USA | 12 | 1/1.41(1.044-1.904) | N/A |
Prat,2008 | 96 | Spain | 10 | 6.0(0.0002) | 2.15(0.0081) |
Park,2011 | 267 | Korea | <12 | reference | N/A |
12-18 | 1/1.68(1.11-2.56) | N/A | |||
18-35 | 1/2.85(1.70-4.76) | N/A | |||
Altena,2010 | 331 | Netherlands | 5 | 1.62 (95% CI, 1.03-2.54) | 1.75 (95% CI, 1.20-2.57) |
Kim,2008 | 123 | Korea | <10, | reference | reference |
10-21, | 1/2.396(1.270-4.521) | 1/2.508(1.062-5.921) | |||
>21 | 1/5.384(2.510-11.549) | 1/3.929(1.140-8.607) | |||
Crawford,2005 | 78 | UK | 10 | 1/D.1336(p<0.001) | N/A |
Grad,1994 | 223 | Australia | 15 | 1/3.23(2.62-3.99) | N/A |