Table 1. Output of ESEfinder program when the wild-type and mutated PLP1 exon 3B sequences are compared.
Sequence | Splicing factor motif | Score | Threshold score |
---|---|---|---|
TGGCTA (Wt) | SRSF6 | 0.40451 | 2.676 |
TGGGTA (M) | 2.70848 | ||
TGGG AA (DM) | 0.10328 |
Legend: the mutated nucleotides are underlined; Wt = wild-type; M = mutant; DM = double mutant.