Table 3. Comparison of human and zebrafish neutrophil proteomes based on subcellular localization (a) and on association with biological process (b).
Subcellular localization (a) | ||
Compartment | Human | Zebrafish |
Cytoplasm | 19% | 19% |
Macromolecular complex | 5% | 10% |
Intracellular organelles | 10% | 3% |
Extracellular | 6% | 2% |
Cell surface | 1% | – |
Plasma membrane | 11% | 3% |
Cytoskeleton | 6% | 7% |
Peroxisome | 1% | – |
Nucleus | 13% | 17% |
Mitochondria | 7% | 5% |
ER | 4% | 4% |
Ribosome | – | 8% |
Chromosome | 2% | 3% |
Endosome | 4% | 1% |
Others | 11% | 19% |
Biological process (b) | ||
Process | Human | Zebrafish |
Regulation | 21% | 19% |
Reproduction | 3% | – |
Response to stimulus | 7% | 3% |
Cellular process | 27% | 44% |
Developmental process | 6% | 7% |
Growth | 2% | – |
Immune system process | 5% | 1% |
Interaction with cells and organism | 7% | 2% |
Localization | 6% | 6% |
Metabolic process | 8% | 11% |
Other | 12% | 8% |