Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Panels A to D show that leptin upregulates gene and protein expression of JAK2 (A,B), gene expression of STAT3 (C) and protein levels of p-STAT3 (D). Panels E to H show that leptin-induced upregulation of FTO is prevented by the JAK inhibitor AG490 (E,F) and the STAT3 inhibitor S31–201 (S31, G,H). Data are presented as mean+SEM, N = 8 *P<0.05 from control group not treated with leptin.
