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. 2013 Sep 3;8(9):e74235. doi: 10.1371/journal.pone.0074235

Figure 6. Suppression of CUX1 prevents leptin-induced FTO upregulation.

Figure 6

Immunofluorescent images and corresponding quantified immunofluorescence intensity data showing that CUX1 siRNA (+siCUX1) supressed basal FTO expression and completely prevented the effect of leptin on FTO. Quantitative data are presented as mean +SEM. N = 7. *P<0.05 from respective control group; +P<0.05 from respective group in the absence of siCUX1 (−siCUX1). Horizontal bar in bottom right images indicates 200 µm.