Table 4. Analysis of Molecular Variance (AMOVA) of Asian C. neoformans according to HIV status and geographical origin.

	d.f.	Sum of Squares	Variance components (%)	p-value
Clinical isolates: HIV-positive (n = 227), HIV-negative(n = 135), unknown HIV status (n = 47)
Among populations	2	109.66	0.44 (11.62)
Within populations	406	1364.16	3.36 (88.38)
Total	408	1473.82	3.80 (100)	0.0000
Isolates from HIV-positive patients : East Asia (n = 8), Middle East (n = 5), South/Southeast Asia (n = 214)
Among populations	2	14.37	0.30 (7.95)
Within populations	224	775.92	3.46 (92.05)
Total	226	790.29	3.76 (100)	0.0654±0.0025
Isolates from HIV-negative patients : East Asia (n = 99), Middle East (n = 10), South/Southeast Asia (n = 26)
Among populations	2	199.54	3.39 (63.20)
Within populations	132	260.46	1.97 (36.80)
Total	134	460.00	5.36 (100)	0.0000