Table 7. Linkage disequilibrium analysis amongst Asian C. neoformans var. grubii populations.
Linkage Disequilibrium | |||||
Population | Sample type | IA | p-value | rBarD | p-value |
East Asia | all isolates (n = 138) | 1.750 | <0.001 | 0.397 | <0.001 |
clone- corrected (n = 11) | 0.494 | 0.018 | 0.100 | 0.018 | |
Middle East | all isolates (n = 15) | 0.433 | 0.043 | 0.073 | 0.043 |
clone- corrected (n = 10) | 0.178 | 0.272 | 0.030 | 0.272 | |
South/Southeast Asia | all isolates (n = 323) | 1.462 | <0.001 | 0.295 | <0.001 |
clone-corrected (n = 22) | 0.857 | <0.001 | 0.144 | <0.001 | |
Overall | all isolates (n = 476) | 0.007 | <0.001 | 0.002 | <0.001 |
clone- corrected (n = 28) | 0.901 | <0.001 | 0.151 | <0.001 |
IA: Index of Association.
rBarD: a modified statistics for multilocus linkage disequilibrium analysis.