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. 2013 Sep 3;8(9):e73088. doi: 10.1371/journal.pone.0073088

Figure 3. Microparticles (MPs) from CD patients impair endothelium-dependent relaxation in mouse aorta.

Figure 3

Acetylcholine (Ach)-induced relaxation in aortic rings isolated from mice injected in vivo with vehicle (controls (CTL)), MPs from HS (HSMPs) and MPs from CD patients (CDMPs) (A) subsequently separated in inactive CD patients (inactive CDMPs) (B) and active CD patients (active CDMPs) (B). Results are expressed as a percentage of U46619-induced pre-contraction and given as mean ± SEM (n = 5–11). ***p<0.001 vs CTL; ††† p<0.001 vs HSMPs; $$$ p<0.001 active CDMPs vs inactive CDMPs.