Table 1. Clinical characteristics of Crohn’s disease (CD) patients.
Inactive CD patients (n = 13) | Active CD patients (n = 26) | |
Gender (women/men) | 7/6 | 20/6 |
Age (median, extremes) | 37 (19–59) | 28 (19/60) |
Disease activity: Harvey-Bradshaw index (HB) median (extremes) | HB: 1 (0–3) | HB: 10 (5–21); Non-severe: n = 15; HB: 9 (5–10); Severe: n = 11; HB: 14 (13–21) |
Disease duration (months) (median, extremes) | 108 (17–304) | 84 (0.5–276) |
Type of Crohn’s disease | Inflammatory: n = 9; Stenotic: n = 4 | Inflammatory: n = 22; Stenotic: n = 4 |
Extension | Only ileal: n = 4; Only colonic: n = 4; Ileocolonic: n = 5 | Only ileal: n = 5; Only colonic: n = 10; Ileocolonic: n = 11 |
Perineal disease (yes/no) | 4/9 | 7/19 |
Treatment* | No treatment: n = 0; Corticosteroids: n = 7; Azathioprine:n = 3; Methotrexate: n = 1; Anti-TNF mAb**: n = 9 | No treatment: n = 11; Corticosteroids: n = 8; Azathioprine: n = 7; Methotrexate: n = 2; Anti-TNF mAb**: n = 5 |
Previous surgery (ileocolonic resection)*** (yes/no) | 2/11 | 2/24 |
Total is higher than the number of patients as some of them receive combination of medication.
mAb: Monoclonal antibody. All patients, except two in the active CD patients group failing adalimumab therapy at the time of inclusion, received infliximab.
Except ileocolonic resection no patient had underwent other type of small bowel and/or colonic surgery.