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CaMKIIα.FingR-GFP translocates to dendritic spines upon excitatory stimulation. A, CaMKIIα.FingR-GFP expressed in cortical neurons in dissociated culture localizes in a diffuse fashion. B, 54 s after addition of 50 μm glutamate and 5 μm glycine to the bath CaMKIIα.FingR-GFP localizes specifically to puncta corresponding to the tips of dendritic spines. Scale bars, 5 μm.
