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. 2013 Sep 7;19(33):5485–5492. doi: 10.3748/wjg.v19.i33.5485

Figure 6.

Figure 6

Propofol abrogates gemcitabine-induced nuclear factor-κB in MIA-PaCa-2 cells. A: MIA-PaCa-2 cells were exposed to 10-100 μmol/L gemcitabine for 72 h. Nuclear extracts were analyzed by electrophoretic mobility shift assay (EMSA); B: Propofol abrogated gemcitabine induced nuclear factor-κB (NF-κB) in MIA-PaCa-2 cells exposed to 100 μmol/L/mL propofol for 24 h followed by incubation with 100 μmol/L gemcitabine. Nuclear extracts were harvested at 72 h and analyzed by EMSA. Propofol pretreatment downregulated gemcitabine-induced NF-κB with 100 μmol/L gemcitabine.