Figure 6. Effect of SAG on mitochondrial membrane potential. Isolated rat liver mitochondria (0.6 mg/mL) were incubated in standard medium and the ΔΨm was monitored as described in experimental session.
a: Effect of SAG (10-200 mg/mL) on mitochondrial membrane potential; b: values of ΔΨm after adding the mitochondrial uncoupler 2,4-dinitro-phenol (2,4-DNP) point indicated by arrow in a). Experiments were performed three times using independent mitochondrial preparation. Mean±SEM, n=3. * Significant difference vs. control: P<0.05.