Table 2. In vitro antiplasmodial and cytotoxic activities of the crude extract, differents fractions and the pure compound of stem barks of S. leptoclada.
Antiplasmodial activity | Cytotoxicity activity | |
Test | IC50 (µg/mL) | IC50 (µg/mL) |
Acetonic extract | 0.85±0.05 | 0.72±0.02 |
Cyclohexane | 23.17±2.03 | 35.61±1.01 |
Ethyl acetate | 0.35±0.09 | 0.28±0.06 |
n-Butanol | 34.68±1.01 | 43.59±0.82 |
Aqueous | 41.09±1.71 | 51.32±2.01 |
Fraction F2+3 | 0.175±0.05 | 0.15±0.04 |
Fraction F31 | 0.076±0.02 | 0.069±0.03 |
Pure compound | 0.052±0.03 | 0.041±0.02 |