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Effect of MMP-13 on myoblast proliferation measured by 5-bromo-2P-deoxyuridine (BrdU) incorporation. A: MMP-13 inhibitor does not impair proliferation in C2C12 myoblasts in GM. B: stable expression of MMP-13 does not alter proliferation in C2C12 cells in the absence of serum compared with cells stably expressing GFP vector only. Values are means ± SE for 3 separate experiments.
