Fig. 1.

Effect of chronic alcohol feeding on carrier-mediated riboflavin (RF) uptake by rat jejunal brush-border membrane vesicles (BBMV) and basolateral membrane vesicles (BLMV). BBMV (A) and BLMV (B) were prepared from the jejunum of rats that were chronically fed alcohol liquid diet for 4 wk and their pair-fed controls and were briefly incubated at room temperature and then immediately used for uptake assay. [³H]RF (240 nM) was added to the vesicle-containing buffer at the time of the uptake experiment. Data are means ± SE of at least 5–10 independent uptake determinations from multiple sets of rats. *P < 0.01.