Fig. 1.
Transient current in rabbit urethral smooth muscle cells is large-conductance K+ (BK) current. Ai and Aii: families of currents evoked from a holding potential of −80 mV to potentials up to +50 mV in the absence (control) and presence of 300 nM iberiotoxin (IbTx). Aiii: transient and sustained components of the IbTx-sensitive difference currents. B and C: summary current-voltage (I-Vm) relationships for the peak large-conductance K+ current in the absence (control) and presence of IbTx (n = 13) or penitrem A (PenA, n = 5).