Fig. 2.

Transient BK (tBK) current depends on Ca²⁺ influx through L-type Ca_v channels. Ai: effect of Ca²⁺ removal after currents were evoked by steps from −60 to 0 mV. Aii: difference current obtained by digital subtraction of traces in Ai. Aiii: summary data for 8 experiments in which peak tBK current was measured before (control) and after Ca²⁺ removal. B and C: tBK current was also blocked in the presence of nifedipine and Cd²⁺. Bii and Cii: nifedipine- and Cd²⁺-sensitive difference currents. Biii and Ciii: summary data for nifedipine (Nif)- and Cd²⁺ (Cad)-sensitive curents. *P < 0.05, **P < 0.01 (by paired t-test).