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. 2013 Jun 26;305(5):F628–F640. doi: 10.1152/ajprenal.00210.2013

Table 3.

Differentially regulated cytosolic proteins during chronic metabolic acidosis

Protein Name Accession Number Entry Name Gene Name P Value Fold-Change Detection Method
Sodium/potassium-transporting ATPase subunit α-1 P06685 AT1A1_RAT Atp1a1 0.003 0.14 SpC
Low-density lipoprotein receptor-related protein 2 P98158 LRP2_RAT Lrp2 0.010 0.36 SpC
Phosphoenolpyruvate carboxykinase, cytosolic P07379 PCKGC_RAT Pck1 0.012 3.37 SpC
Triosephosphate isomerase P48500 TPIS_RAT Tpi1 0.020 0.54 SpC
Glutathione S-transferase P P04906 GSTP1_RAT Gstp1 0.026 3.15 SpC
Transgelin-2 Q5XFX0 TAGL2_RAT Tagln2 0.027 0.46 SpC
Uncharacterized protein D3ZPL5 D3ZPL5_RAT RGD1562953 0.041 3.07 SpC
N-acylglucosamine 2-epimerase F1LQ78 F1LQ78_RAT Renbp 0.047 0.23 SpC
Acyl-coenzyme A thioesterase 1 O88267 ACOT1_RAT Acot1 0.047 0.48 SpC
d-Dopachrome decarboxylase P80254 DOPD_RAT Ddt 0.031 5.47 TIC
Aromatic l-amino acid decarboxylase P14173 DDC_RAT Ddc 0.016 0.28 TIC
Prostaglandin E synthase 3 P83868 TEBP_RAT Ptges3 0.039 15.86 TIC
Ketohexokinase Q02974 KHK_RAT Khk 0.040 2.09 TIC
Pyruvate carboxylase, mitochondrial P52873 PYC_RAT Pc 0.045 2.05 TIC

Proteins in bold and italics were previously identified to exhibit altered expression during chronic acidosis (7, 10, 31, 43).