Table 2.
Serum and urine measurements in WT and AMPK-β1−/− mice fed a Na+-deficient diet
| WT Mice | AMPK β1−/− Mice | Number of Animals | P Value | |
|---|---|---|---|---|
| Serum measurements after 7 days | ||||
| Na+, mmol/l | 168.9 ± 18.0 | 171.4 ± 14.4 | 11 | 0.256 |
| K+, mmol/l | 6.7 ± 1.7 | 7.4 ± 2.7 | 11 | 0.198 |
| Cl−, mmol/l | 106.5 ± 7.5 | 104.5 ± 5.3 | 11 | 0.158 |
| PO43−, mmol/l | 3.13 ± 0.74 | 2.8 ± 1.2 | 11 | 0.086 |
| Creatinine, mmol/l | 0.028 ± 0.00 | 0.029 ± 0.00 | 11 | 0.495 |
| Urine measurements after 2 days | ||||
| Creatinine, mmol/l | 2.81 ± 0.86 | 2.45 ± 1.35 | 10 | 0.472 |
| Ratio of mmol/mmol creatinine | ||||
| Na+ | 4.49 ± 1.04 | 5.58 ± 2.92 | 10 | 0.341 |
| K+ | 25.6 ± 7.3 | 34.6 ± 12.7 | 10 | 0.062 |
| Cl− | 6.73 ± 1.98 | 10.4 ± 1.7 | 10 | 0.478 |
| Ca2+ | 0.42 ± 0.27 | 0.37 ± 0.13 | 10 | 0.596 |
| Mg2+ | 2.45 ± 0.40 | 1.83 ± 0.98 | 7 | 0.189 |
| PO43− | 24.1 ± 13.7 | 31.1 ± 10.3 | 10 | 0.203 |
| Urea | 265.5 ± 63.3 | 275.2 ± 26.8 | 10 | 0.758 |
Values are means ± SD.