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. Author manuscript; available in PMC: 2013 Sep 4.
Published in final edited form as: J Biol Chem. 2005 Jan 15;280(10):8637–8639. doi: 10.1074/jbc.C500017200

Table II.

Mutations that affect tgm silencing and ribosomal RNA biosynthesis

Gene name Functions
Δrpa12 Subunit of RNA polymerase I, nucleolar localization
Δrpa49 Subunit of RNA polymerase I, nucleolar localization
Δrrn10 Component of the upstream activation factor complex, activation of RNA pol I; null mutant shows defective RNA pol I transcription and defective RNA pol II silencing at the rRNA gene locus
Δuaf30 Component of the upstream activation factor complex, nucleolar localization, activation of RNA pol I; null mutant shows defect of RNA pol II transcription silencing at the rRNA gene locus
cbf5-1 rRNA pseudouridine synthase, nucleolar protein found in H/ACA snoRNP complexes; it was previously shown that cbf5-1 disorganizes pre-tRNA location and mildly disorders nucleolus (Ref. 6)