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Microorganisms in the mesohyl of C. crambe embedded in the collagen matrix of the sponge, (a). Proximity between microorganisms and spherulous cells, (b–c). Bacteria in division, (d). C: collagen; Er: endoplasmic reticulum; mi: mitochondrion; M: Microorganisms; n: nucleus; S:sponge cell; Sc: Spherulous cell whose vesicles (V) contain an electron dense material.
