Figure 1.
The nuclear pore complex (NPC). Schematic representation of a cross-section view of a NPC as it spans the inner (INM) and outer (ONM) nuclear membranes. Vertebrate Nups are listed based on their localization within the NPC. The central core (green) is composed of the inner-ring Nups, transmembrane Nups, linker Nups, outer-ring Nups and the phenylalanine-glycine (FG)-Nups. The location of select nucleoporins within the NPC is shown.