Table 1.

Unadjusted Analysis of the Association of Various Demographic and Clinical Factors Relative to Acquisition of Candida krusei and C glabrata

Characteristic	Non-CGCK Candida Species (n = 321)	CGCK (n = 23)	P Value*
Patient characteristics
Age in years	3.48 (1.11, 11.93)	9.27 (4.32, 13.80)	.017
Age > 2 years	206 (64%)	21 (91%)	.006
Male	8 (35%)	182 (57%)	.051
Length of hospital stay in days	34 (16, 69)	25 (15, 44)	.327
Time to infection	13 (4, 25)	12 (0, 27)	.487
Length of stay following infection	18 (9, 38)	15 (6, 25)	.219
Admitted to the ICU at diagnosis	132 (41%)	6 (26%)	.189
Comorbidities and clinical procedures
Receipt of a prior bone marrow or solid organ transplantation	30 (9%)	5 (22%)	.071
Malignancy	97 (30%)	12 (52%)	.037
Dialysis (peritoneal/hemodialysis)	11 (3%)	1 (4%)	.570
Clinical features 48 hours prior to a positive blood culture for Candida
Mechanical ventilation	85 (26%)	6 (26%)	>.999
Clinical features within 1 week prior to a positive blood culture for Candida
Presence of a central venous catheter	293 (91%)	21 (91%)	>.999
Presence of an arterial catheter	77 (24%)	5 (22%)	>.999
Presence of a urinary catheter	78 (24%)	6 (26%)	.805
Receipt of total parenteral nutrition	182 (57%)	18 (78%)	.049
Clinical features within 15 days of study entry
Receipt of a surgical procedure	75 (23%)	10 (43%)	.043
Neutropenia	53 (17%)	7 (30%)	.149
Non-candidal bloodstream infection	114 (36%)	7 (30%)	.822
Medication use within 15 days of study entry
Receipt of antibiotics	290 (90%)	21 (91%)	>.999
Receipt of immunosuppressive agents	113 (35%)	7 (30%)	.821
Receipt of fluconazole	33 (10%)	8 (35%)	.003
Receipt of antifungal agents other than fluconazole	35 (11%)	3 (13%)	.730

*P values obtained using Fisher's exact test for categorical variables and Wilcoxon rank-sum test for continuous variables.

CGCK, C glabrata or C krusei; ICU, intensive care unit.