. Author manuscript; available in PMC: 2014 Sep 15.

Published in final edited form as: Bioorg Med Chem Lett. 2013 Jul 8;23(18):5209–5212. doi: 10.1016/j.bmcl.2013.06.093

Table 2.

Aqueous Solubility at pH 6.5 (S)

Compound	S, μg/mL	Compound	S, μg/mL
2a	0.1	efavirenz	68.0
2j	42.2	dapivirine	0.15
2k	52.3	rilpivirine	0.24^a, 0.02^b

Ref. 18, pH 7.4.

Ref. 20, pH 7.