. Author manuscript; available in PMC: 2014 Jul 26.

Published in final edited form as: J Nat Prod. 2013 Jul 15;76(7):1369–1375. doi: 10.1021/np400435t

Table 1.

¹H NMR Data (δ in ppm, J in Hz) for Compounds 1–5 in CDCl₃

position	1^a	2^b	3^b	4^b	5^c
1	4.74 (1H) d (5.5)	4.61 (1H) d (5.2)	4.79 (1H) d (4.6)	4.78 (1H) d (5.0)	3.74 (1H) t (6.4)
1-OH					2.24 (1H) m
2	3.47 (1H) dd (5.5, 3.6)	3.51 (1H) dd (4.1, 4.1)	3.74 (1H) br	3.77 (1H) t (4.1)	3.43 (1H) dd (5.4, 3.5)
3	3.38 (1H) m	3.40 (1H) m	3.62 (1H) m	3.61 (1H) br	3.57 (1H) m
4	2.21 (2H) m	2.22 (2H) m	2.48 (1H) d (15.8) 2.32 (1H) d (16.3)	2.48 (1H) d (16.7) 2.32 (1H) d (16.7)	2.19 (2H) m
5	2.70 (1H) m	2.67 (1H) dd (10.4, 5.5)			2.51 (1H) dd (10.8, 5.5)
5-OH			3.46 (1H) s	3.43 (1H) s
7	4.31 (1H) m	4.16 (1H) d (10.0)	4.67 (1H) dd (10.9, 2.6)	4.67 (1H) brd (10.0)	3.97 (1H) d (10.2)
7-OH	3.95 (1H) d (3.4)	3.88 (1H) br	4.04 (1H) d (2.6)	4.06 (1H) brs	4.37 (1H) br
8	1.78 (1H) t (11.0)	1.78 (1H) m	1.59 (1H) m	1.58 (1H) m	1.68 (1H) m
9	2.76 (1H) t (11.4)	2.21 (1H) m	2.67 (1H) m	2.67 (1H) dt (12.0, 3.7)	2.23 (1H) m
11	5.35 (1H) dd (2.7, 11.4)	2.17 (1H) 1.72 (1H) m	1.63 (2H) m	1.62 (2H) m	1.60 (2H) m
12	5.27 (1H) d (2.8)	5.02 (1H) br	4.94 (1H) br	4.96 (1H) br	5.02 (1H) m
14	2.58 (1H) dd (11.1, 7.2)	2.47 (1H) dd (11.0, 7.2)	2.15 (1H) m	2.14 (1H) m	2.08 (1H) m
15	5.38 (1H) dd (7.2, 9.5)	5.27 (1H) dd (8.6, 7.4)	4.39 (1H) dd (9.7, 9.7)	4.39 (1H) t (10.0)	4.38 (1H) t (9.8)
15-OH			5.11 (1H) br	5.13 (1H) d (3.7)	5.16 (1H) d (2.4)
16	2.12 (1H) m	2.12 (1H) m	2.38 (1H) dd (12.2)	2.38 (1H) t (12.3)	2.39 (1H) dd (13.4, 10.4)
17	2.91 (1H) dd (13.3, 10.8)	3.00 (1H) dd (13.3, 11.1)	2.00 (1H) dd (11.9)	2.00 (1H) m	2.00 (1H) dd (13.0, 9.5)
18	0.97 (3H) s	0.85 (3H) s	0.81 (3H) s	0.81 (3H) s	0.83 (3H) s
19	0.79 (3H) s	0.75 (3H) s	0.72 (3H) s	0.73 (3H) s	0.64 (3H) s
20	1.75 (1H) m	1.79 (1H) m	2.20 (1H) m	2.19 (1H) m	2.20 (1H) m
21	0.84 (3H) d (6.4)	0.88 (3H) d (6.4)	0.95 (3H) d (7.2)	0.95 (3H) d (7.0)	0.97 (3H) d (7.0)
22	2.52 (1H) dd (16.2, 4.4) 2.27 (1H) m	2.52 (1H) dd (16.6, 4.6) 2.33 (1H) dd (16.6, 12.4)	5.02 (1H) br	5.02 (1H) s	5.02 (1H) m
25-OH			4.70 (1H) s	4.73 (1H) s	4.72 (1H) s
27	1.48 (3H) s	1.49 (3H) s	1.68 (3H) s	1.67 (3H) s	1.68 (3H) s
28	1.23 (3H) s	1.26 (3H) s	1.37 (3H) s	1.37 (3H) s	1.37 (3H) s
1-OAc	2.20 (3H) s	2.14 (3H) s	2.09 (3H) s
11-OAc	2.00 (3H) s
12-OAc	2.13 (3H) s	2.15 (3H) s	2.10 (3H) s	2.11 (3H) s	2.09 (3H) s
2′				2.19 (2H) m
3′				2.12 (1H) m
4′				1.02 (3H) d (6.8)
5′				1.00 (3H) d (6.8)

600 MHz

700 MHz

500 MHz