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NCI-Organ Dysfunction Working Group liver and renal dysfunction classification table.
| Group | TB Value | AST Value |
|---|---|---|
| Normal | ≤ ULN and | ≤ULN |
| Mild | 1-1.5 × ULN or | > ULN |
| Moderate | 1.5-3 × ULN and | Any |
| Severe | 3-10 × ULN and | Any |
|
| ||
| NCI-ODWG Renal Dysfunction Classification | ||
|
| ||
| Group | Creatinine Clearance | |
|
| ||
| Normal | ≥ 60 mL/min | |
| Mild | 40-59 mL/min | |
| Moderate | 20-39 mL/min | |
| Severe | < 20 mL/min | |
Abbreviations: AST, aspartate aminotransferase; TB, total bilirubin; ULN, upper limit of normal.
