. Author manuscript; available in PMC: 2013 Sep 4.

Published in final edited form as: Trends Neurosci. 2006 Mar 7;29(4):233–240. doi: 10.1016/j.tins.2006.02.006

Table 2. Phenotypic assay systems used in high-throughput neuroscience screens.

Phenotypic domain	Assay	Notes	Software package
Circadian rhythm	Wheel-running behavior	Described in [70]	ClockLab^a
Learning and memory	Fear conditioning	Video-image-based scoring of freezing	FreezeFrame^a
Preliminary assessment	Open-field activity	Video-image-based scoring of exploration	LimeLight^a
Preliminary assessment	Elevated plus maze	Video-image-based scoring of exploration	LimeLight^a
Psychostimulant response	Hyperlocomotion behavior	Video-image-based tracking of locomotion	BigBrother^a
Vision	Electroretinogram	Described in [20]	Developed by Lawrence Pinto and colleagues
Vision	Fundus photography	Described in [20]	Not applicable

Software from Actimetrics Inc. (http://www.actimetrics.com/).