Table 3.
Analysis of Differences Among Groups
| |
FA |
MD |
||||
|---|---|---|---|---|---|---|
| WC | Mild | Moderate | Severe | Mild | Moderate | Severe |
| Control | 0.274 | 0.233 | <0.001 | <0.001 | <0.001 | <0.001 |
| Mild | - | 1.000 | 0.001 | - | <0.001 | <0.001 |
| Moderate | - | 0.001 | - | <0.001 | ||
| LD | RD | |||||
|---|---|---|---|---|---|---|
| Control | 0.004 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| Mild | - | <0.001 | <0.001 | - | 0.039 | <0.001 |
| Moderate | - | <0.001 | - | <0.001 | ||
| |
FA |
MD |
||||
|---|---|---|---|---|---|---|
| VWM | Mild | Moderate | Severe | Mild | Moderate | Severe |
| Control | 0.977 | 0.017 | <0.001 | 0.039 | <0.001 | <0.001 |
| Mild | - | 0.050 | <0.001 | - | <0.001 | <0.001 |
| Moderate | - | 0.065 | - | 0.061 | ||
| LD | RD | |||||
|---|---|---|---|---|---|---|
| Control | 0.760 | 0.001 | <0.001 | 0.914 | <0.001 | <0.001 |
| Mild | - | 0.016 | <0.001 | - | <0.001 | <0.001 |
| Moderate | - | <0.001 | - | <0.001 | ||
| |
FA |
MD |
||||
|---|---|---|---|---|---|---|
| DWM | Mild | Moderate | Severe | Mild | Moderate | Severe |
| Control | 0.516 | 0.182 | <0.001 | <0.001 | <0.001 | <0.001 |
| Mild | - | 0.006 | <0.001 | - | <0.001 | <0.001 |
| Moderate | - | 0.014 | - | 0.707 | ||
| LD | RD | |||||
|---|---|---|---|---|---|---|
| Control | 0.728 | 0.004 | <0.001 | <0.001 | <0.001 | <0.001 |
| Mild | - | 0.066 | <0.001 | - | <0.001 | <0.001 |
| Moderate | - | 0.001 | - | <0.001 | ||
| |
FA |
MD |
||||
|---|---|---|---|---|---|---|
| LWM | Mild | Moderate | Severe | Mild | Moderate | Severe |
| Control | 0.842 | 0.144 | <0.001 | 0.989 | <0.001 | <0.001 |
| Mild | - | 0.020 | <0.001 | - | <0.001 | <0.001 |
| Moderate | - | 0.074 | - | 0.052 | ||
| LD | RD | |||||
|---|---|---|---|---|---|---|
| Control | 0.647 | 0.441 | <0.001 | 0.001 | <0.001 | <0.001 |
| Mild | - | 0.046 | <0.001 | - | <0.001 | <0.001 |
| Moderate | - | <0.001 | - | <0.001 | ||
| |
FA |
MD |
||||
|---|---|---|---|---|---|---|
| GM | Mild | Moderate | Severe | Mild | Moderate | Severe |
| Control | 0.325 | 0.148 | 0.015 | 0.136 | <0.001 | <0.001 |
| Mild | - | 0.972 | 0.515 | - | <0.001 | <0.001 |
| Moderate | - | 0.781 | - | 0.064 | ||
| LD | RD | |||||
|---|---|---|---|---|---|---|
| Control | 0.308 | 0.807 | <0.001 | 0.084 | <0.001 | <0.001 |
| Mild | - | 0.829 | <0.001 | - | <0.001 | <0.001 |
| Moderate | - | <0.001 | - | <0.001 | ||
The differences among group means for each severity group are shown above. P values from analysis of variance (ANOVA) results for the differences between each of the severity groups for each diffusion tensor imaging (DTI) metric are shown for whole cord (WC), ventral white matter (VWM), dorsal white matter (DWM), lateral white matter (LWM), over all white matter (WM) and overall gray matter (GM) region of interest drawings (ROIs). Comparisons were made for the fractional anisotropy (FA), mean diffusivity (MD), longitudinal diffusivity (LD), and the radial diffusivity (RD) diffusion metrics.