Table 1.
Mechanoresponsive Genes Significantly Upregulated in Treatment Group Day 7–13 Relative to Controls
| HGNC agreed gene symbol | Description | Fold upregulation |
|---|---|---|
| ALPL | Alkaline phosphatase, liver/bone/kidney | 180.30 |
| BGLAP | Bone γ-carboxyglutamate (gla) protein (Osteocalcin) | 168.60 |
| BMP1 | Bone morphogenetic protein 1 | 20.42 |
| BMP4 | Bone morphogenetic protein 4 | 21.74 |
| BMP5 | Bone morphogenetic protein 5 | 34.29 |
| BMP6 | Bone morphogenetic protein 6 | 26.31 |
| GDF10 | Growth differentiation factor 10 | 896.43 |
| RUNX2 | Runt-related transcription factor 2 | 469.43 |
| SMAD2 | SMAD family member 2 | 138.71 |
| SOX9 | SRY (sex determining region Y)-box 9 | 92.76 |
| TGFB1 | Transforming growth factor, beta 1 | 11.35 |
| TGFB2 | Transforming growth factor, beta 2 | 11.41 |
| TGFB3 | Transforming growth factor, beta 3 | 56.90 |
| VDR | Vitamin D (1,25-dihydroxyvitamin D3) receptor | 88.10 |
HGNC, Human Genome Organization Gene Nomenclature Committee.