Skip to main content
. 2013 Jun 17;19(19-20):2138–2146. doi: 10.1089/ten.tea.2012.0575

FIG. 3.

FIG. 3.

Effect of NGF on neurite outgrowth from DRG explants. (I) Sum of the lengths of the 10 longest neurites from murine DRGs grown on aligned nanofiber scaffolds in media (light bars) or 4C+4H hydrogel (dark bars) with the indicated concentrations of NGF. Least square means±SEM are shown. At all NGF concentrations, neurite outgrowth was significantly greater for DRGs grown in hydrogel compared to media (p<0.0001). Different letters over the hydrogel groups indicate significant differences in neurite lengths (p<0.05). (II) Representative immunofluorescence images: DRG explants cultured on aligned nanofiber scaffolds with NGF. A–D show NGF delivery in media (A: 0 ng/mL; B: 20 ng/mL; C: 100 ng/mL; D: 500 ng/mL). E–H show NGF delivery in 4C+4H hydrogel (E: 0 ng/mL; F: 20 ng/mL; G: 100 ng/mL; H: 500 ng/mL).