Figure 1.
(a) Serum anti-gp140 (glycoprotein 140) immunoglobulin G (IgG) antibody titers after a single cycle of intravaginal administration of 9×65 μg doses of gp140 (Group D) or 9×100 μg doses of gp140 (Group A). The limit of detection is shown as a horizontal dashed line. Box plots show 25th and 75th percentiles, error bars show 10th and 90th percentiles, (…) show mean and (—) show median titers of the groups. NT is not tested. (b) Serum virus infectivity neutralizing activity against human immunodeficiency virus (HIV)-1 clade C tier 1 (MW965.26) and tier 2 (96ZM651.02) pseudovirus detected in Group A animals.