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. Author manuscript; available in PMC: 2013 Sep 4.
Published in final edited form as: Hepatology. 2010 Jan;51(1):130–141. doi: 10.1002/hep.23292

Figure 4. IL-12 is involved in steatosis-associated hepatic NKT cell depletion.

Figure 4

C57BL/6 (Wt) and Interleukin (IL)-12−/− mice were fed CDD for 0, 10 or 20 weeks and total liver mononuclear cells were analyzed by flow cytometry. Hepatic mononuclear cells (A) or splenocytes (C) were stained with anti-mouse T cell receptor β (TCR) and natural killer (NK) 1.1 antibodies. T cells, NKT cells and NK cells are outlined in boxes. Values represent percent of total liver mononuclear cells analyzed. B and D. Quantitation of hepatic (B) or splenic (D) NKT cells expressed as percent of total hepatic CD3+ cells expressing NK1.1. Figure is representative for 3-6 different experiments. Results are representative of 3-6 animals per group.