Table 2.

Sensitivity and specificity of various diagnostic tools used in CJD^{2 5 7 8}

Diagnostic tool	Sensitivity (%)	Specificity (%)
EEG (periodic triphasic sharp wave complexes)	44	92
CSF 14-3-3 protein found in CSF (qualitative western blot)	90	40
Tau protein found in CSF (quantitative ELISA test/cutpoint 1150 pg/mL)	87	67
Current WHO criteria	92	71.2
MRI-CJD consortium 2009 criteria	98	70.8
UCSF 2010 MRI criteria	98	100
Our suggested updated criteria	To be evaluated

CJD, Creutzfeldt-Jacob disease; CSF, cerebrospinal fluid; UCSF, University of California, San Francisco.