Table 1.

Components of the CLUE Protocol.

Signs	Probe site	Diagnostic targets	Normal	Abnormal
LVSD	Parasternal long axis	Distance from the anterior leaflet of the mitral valve to the septum during diastole	≤1 cm	>1 cm
LAE	Parasternal long axis	Anteroposterior diameter of the LA versus overlying aorta throughout the cardiac cycle	Aorta > LA	LA > Aorta
ULC+	Bilateral lung apices	Number of lung comets in either lung apex	<3	≥3
eCVP	Subcostal	Percent luminal diameter reduction of IVC with respiration, without forced “sniffing”	>50%	≤50%