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. Author manuscript; available in PMC: 2013 Dec 21.
Published in final edited form as: Science. 2013 May 9;340(6139):1456–1459. doi: 10.1126/science.1237013

Fig. 2. GPR15 mediates T cell homing to the LILP.

Fig. 2

(A) Ratio of Gpr15-transduced and control-transduced donor cells in different tissues (MLN: Mesenteric lymph nodes; PLN: Inguinal, Brachial, and Axillary lymph nodes) at 10h after transfer of an equal number of cells (n=6, combined from three independent experiments). (B) Ratio of Gpr15-transduced cells treated with PTX and untreated control-transduced cells after co-transfer (n=5). (C) Ratio of cells transduced with control vector and the R131A mutant Gpr15 fused with gfp (GPR15mut-GFP) (n=7, combined from three independent experiments). (D) Ratio in different tissues of CD4+ T cells from Gpr15gfp/+(Het) and Gpr15gfp/gfp (KO) mice after in vitro culture in GPR15-inducing conditions and transfer of equal numbers of cells into recipients (n=5, combined from two independent experiments). *p<0.05 (t-test).