KZ-41 reduces ICAM-1. (A) ICAM-1 ELISA results for REC treated with nothing, melphalan only, or melphalan + KZ-41 (10 μM). (B) ICAM-1 Western blot results for REC untreated, melphalan only, KZ-41, or Melphalan + KZ-41. In both ELISA and Western blot results, KZ-41 reduced melphalan-induced ICAM-1 levels in REC. *P < 0.05 versus control. #P < 0.05 versus melphalan only. Data are mean ± SEM. n = 4.