Figure 4. .

The role of NF-κB in the regulation of ICAM-1. (A) Western blot results for the ratio of phospho-NF-κB to total NF-κB after melphalan treatment. (B) Western blot results for ratio of phospho-NF-κB to total NF-κB after melphalan and KZ-41 treatments. (C) A control experiment to demonstrate that NF-κB siRNA was able to significantly reduce NF-κB protein levels. (D) ICAM-1 ELISA results after melphalan and NF-κB siRNA treatment. *P < 0.05 versus control. #P < 0.05 versus melphalan only. Data are mean ± SEM. n = 4 for all experiments.