Skip to main content
. 2013 Sep 3;54(9):5937–5943. doi: 10.1167/iovs.13-12326

Figure 6.

Figure 6

Cell death is regulated by KZ-41 and p38 inhibitors. (A) Shows that melphalan regulates ICAM-1 levels in REC and that ICAM-1 siRNA is effective. (B) Cell Death ELISA to demonstrate that melphalan regulates REC apoptosis through ICAM-1 actions. (C) Cell Death ELISA to demonstrate that KZ-41 blocks melphalan-induced apoptosis through p38 MAPK actions. (D) Cell Death ELISA to demonstrate that NF-κB siRNA could not significantly reduce melphalan-induced REC apoptosis. *P < 0.05 versus control. #P < 0.05 versus melphalan. $P < 0.05 versus KZ-41. Data are mean ± SEM. n = 4 for all experiments.