Table 3.
Risk factor | Cases n | Person years n | Q5 v Q1 | P for trend | P for interaction |
---|---|---|---|---|---|
Age | |||||
<55 years | 350 | 1540444 | 0.71 (0.50–1.03) | 0.16 | |
≥ 55 years | 55 | 110807 | 0.49 (0.22–1.12) | 0.07 | 0.42 |
BMI mg/kg2 | |||||
<25 | 123 | 823965 | 0.60 (0.33–1.09) | 0.10 | |
≥ 25 | 282 | 827287 | 0.73 (0.49–1.09) | 0.20 | 0.60 |
Smoking | |||||
never | 173 | 1010830 | 0.53 (0.31–0.92) | 0.04 | |
past | 91 | 375119 | 0.99 (0.51–1.91) | 0.91 | |
current | 141 | 265302 | 0.75 (0.42–1.34) | 0.47 | 0.73 |
Physical activity | |||||
< median | 259 | 825374 | 0.72 (0.47–1.11) | 0.19 | |
> median | 146 | 825877 | 0.63 (0.36–1.08) | 0.12 | 0.68 |
Alcohol | |||||
Non-drinker | 204 | 668944 | 0.75 (0.46–1.25) | 0.61 | |
Drinker | 201 | 982307 | 0.60 (0.38–0.94) | 0.03 | 0.26 |
Prevalent hypertension | |||||
No | 231 | 1398692 | 0.76 (0.49–1.18) | 0.33 | |
Yes | 174 | 252560 | 0.59 (0.35–1.00) | 0.05 | 0.53 |
History of diabetes | |||||
No | 336 | 1609342 | 0.65 (0.45–0.95) | 0.04 | |
Yes | 69 | 41910 | 0.80 (0.34–1.86) | 0.77 | 0.57 |
Multivariate model adjusted for age, physical activity, smoking, BMI, alcohol, energy, menopausal status, PMH use, aspirin use, oral contraceptive use, family history of myocardial infarction, Cereal fiber, saturated fatty acids, trans fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, caffeine