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. Author manuscript; available in PMC: 2013 Sep 4.
Published in final edited form as: Nature. 2012 Dec 23;493(7434):694–698. doi: 10.1038/nature11779

Figure 2. Phylogenetic clusters of candidate small RNA pathway proteins.

Figure 2

Validated miRNA and siRNA pathway proteins map non-randomly on the phylogenetic profile; proteins that map to the same clusters are likely to function in small RNA pathways. Left panel: Clusters enriched for validated miRNA and siRNA pathway proteins, black boxes. Darker blue represents higher protein sequence similarity. Right panel: Pairwise local protein sequence alignment of all pairs of proteins in the cluster; black represents significant similarity and white no similarity.