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. Author manuscript; available in PMC: 2013 Sep 4.
Published in final edited form as: Nat Immunol. 2009 Oct 4;10(11):1162–1169. doi: 10.1038/ni.1797

Figure 5.

Figure 5

Thymocytes downregulate miR-181a in response to selection signals. (a) Quantitative real-time PCR analysis of mature miR-181a in lysates of 5C.C7 Ii-deficient thymocytes allowed to interact for 1 h with plate-bound MCC–I-Ek or GP–I-Ek complexes or with no protein. Results are presented relative to expression in response to no protein, set as 100. Data represent two independent experiments (error bars, s.d.). (b) Quantitative real-time PCR analysis of miR-181a in DP 5C.C7 TCR–transgenic Ii-deficient thymocytes (5C.C7 Ii-KO) and 5C.C7 TCR–transgenic B10.BR thymocytes (5C.C7 B10.BR). Results are presented relative to expression in 5C.C7 Ii-KO thymocytes, set as 100. Data represent two independent experiments (error bars, s.d.).