Table 1.
Summary of outcomes following induction and salvage therapy, overall and by frontline treatment. The sample median of each transition time is given in days, with lower and upper 95% confidence interval limits subscripted on the left and right.
| Group | Initial Outcomes Following Induction Therapy
|
Total N | |||||
|---|---|---|---|---|---|---|---|
| Death | Resistant Disease | CR | |||||
| N (%) | TD | N (%) | TR | N (%) | TC | ||
| All Patients | 69 (33) | 222432 | 39 (19) | 515970 | 102 (48) | 303234 | 210 |
| FAI | 17 (31) | 212752 | 17 (31) | 416397 | 20 (37) | 293144 | 54 |
| FAI+ATRA | 15 (28) | 182244 | 13 (24) | 555976 | 26 (48) | 293144 | 54 |
| FAI+G | 20 (38) | 223245 | 4 (8) | 2777112 | 28 (54) | 293640 | 52 |
| FAI+G+ATRA | 17 (34) | 142130 | 5 (10) | 485170 | 28 (56) | 283238 | 50 |
| Outcomes Following CR or Resistant Disease
|
||||||||
|---|---|---|---|---|---|---|---|---|
| Death After Res | Death in CR | Prog After CR | Death After Prog | |||||
| N (%) | TRD | N (%) | TCD | N (%) | TCP | N (%) | TPD | |
| All Patients | 37 (95) | 6279148 | 9 (9) | 46293345 | 93 (91) | 190256329 | 83 (93) | 106128175 |
| HDAC | 25 (93) | 2765117 | – | – | – | – | 47 (89) | 6298253 |
| Other Trt | 12 (100) | 82130252 | – | – | – | – | 36 (90) | 122158191 |