Figure 5.

Proteomes with random populations of negatively and positively charged proteins form smaller clusters than the minimal proteome models, whose protein populations were derived from experimentally observed protein copy numbers. (A-C) The changes in the cluster size during the simulations in three independent runs of minimal proteome models. (D-H) Comparison of the cluster sizes for the minimal proteome versus random proteomes. The comparison indicates that the minimal proteome models have larger cluster sizes during the simulations.