Skip to main content
. Author manuscript; available in PMC: 2014 Jul 17.
Published in final edited form as: J Am Chem Soc. 2013 Jul 9;135(28):10326–10329. doi: 10.1021/ja4055492

Table 4. Ortho-Iodination of Heterocyclic Compoundsa, b,c.

graphic file with name nihms-504176-t0008.jpg
a

Ar = (4-CF3)C6F4.

b

Reaction conditions: 0.10 mmol substrate, 10 mol % Pd(OAc)2, 0.40 mmol I2, 0.24 mmol CsOAc, 0.10 mmol NaHCO3, 50 mg 4 Å molecular sieves and 2.0 mL of solvent in a sealed tube, 16-48 h.

c

Yields of the isolated product.

d

0.2 eq K2S2O8 was used in place of NaHCO3.