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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Arthritis Rheum. 2013 Apr;65(4):10.1002/art.37825. doi: 10.1002/art.37825

Figure 2.

Figure 2

Protein kinase Cβ (PKCβ) deficiency reverses splenomegaly and restores the CD4:CD8 T cell ratio in Sle mice. A, Spleen weights in the indicated mouse strains at age 8 months. B, Representative results of flow cytometric analysis of spleen T cells from 5–6-month-old mice. Cells were stained with CD4 and CD8 antibodies. C and D, Absolute numbers of activated CD69+ cells in the CD4+ T cell population (C) and in the B220+ cell population (D). Results shown in B, C, and D were obtained from the same group of mice. Bars in A, C, and D show the mean ± SD of 5 mice per group (A) and 3 mice per group (C and D). * = P < 0.05; ** = P < 0.01.