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. 2013 Sep 4;8(9):e73447. doi: 10.1371/journal.pone.0073447

Table 1. Baseline characteristics across categories of total white blood cell (WBC) count in subjects who developed cancer and subjects who did not develop cancer during follow-up.

Categories of WBC count (109 cells/L)
P for trend
< 6.4 6.4-8.5 ≥ 8.6
Cancer
Subjects (n) 671 688 361 -
Age (years) 58.5 ± 13.3 58.2 ± 13.6 55.6 ± 12.8 0.002
Sex (female) 49.0 (329) 51.2 (352) 48.5 (175) 0.9
BMI (kg/m2) 25.9 ± 4.0 25.8 ± 4.2 25.3 ± 3.9 0.06
Daily smoking 21.0 (141) 44.0 (303) 70.6 (255) <0.001
Physical activity (hard) 24.7 (164) 21.3 (145) 16.9 (60) 0.003
Self-reported DM 2.7 (18) 3.8 (26) 3.6 (13) 0.3
Self-reported CVD 11.2 (75) 12.4 (85) 9.4 (34) 0.5
Non-cancer
Subjects (n) 8884 9214 4486 -
Age (years) 46.1 ± 14.9 45.7 ± 14.6 43.5 ± 13.1 <0.001
Sex (female) 49.7 (4414) 53.0 (4884) 54.7 (2455) <0.001
BMI (kg/m2) 24.9 ± 3.6 25.3 ± 3.9 25.2 ± 4.0 <0.001
Daily smoking 19.0 (1689) 39.3 (3618) 66.0 (2963) <0.001
Physical activity (hard) 35.3 (3121) 30.1 (2753) 27.4 (1218) <0.001
Self-reported DM 1.3 (118) 1.9 (172) 1.4 (64) 0.3
Self-reported CVD 5.3 (475) 6.4 (592) 5.6 (252) 0.2

The Tromsø Study 1994-2007.

Values are given as mean ± 1 standard deviation or as percentages with absolute numbers in parentheses.

Physical activity (hard) ≥ one hour per week of activity that caused sweating or breathlessness.

BMI = Body mass index

DM = Diabetes mellitus

CVD = Cardiovascular disease