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(A and B) Schematic diagrams of GFI1 promoter fragments cloned into pGL3-basic vector (A) or inserted upstream of the SV40 promoter of the pGL3-promoter vector. (C and D) p53−/− HCT116 cells were transfected with the indicated GFI1 promoter luciferase reporter constructs without or with p53. Luciferase activities were measured 36 hrs after transfection.
